Anti-Inflammatory Milk Matrix

Inclusion Criteria: * Obese (BMI, body mass index ≥30, \<40 kg•m-2) * Age 40-59 * Pre-menopausal * Sedentary/insufficiently active for prior 6 months (mo) * Weight stable for prior 6 mo Exclusion Criteria: * Tobacco, nicotine (patch/gum) use (previous 6 mo) * Alcohol consumption \>10 drinks per week * Metabolic disorders (e.g., Metabolic Syndrome, Diabetes, thyroid diseases) * Cardiovascular disease, arrhythmias * Hypogonadism * Asthma * History of uncontrolled hypertension * Orthopedic injury/surgery (within 1 yr) * Hepatorenal, musculoskeletal, autoimmune, or neurological disease * History of neuromuscular problems * Previous participation in amino acid tracer studies * Predisposition to hypertrophic scarring or keloid formation * Consumption of ergogenic-levels of dietary supplements that may affect muscle mass (e.g., creatine, HMB), insulin-like substances, or anabolic/catabolic pro-hormones (e.g., DHEA) within 6 weeks prior to participation * Consumption of thyroid, androgenic, or other medications known to affect endocrine function * Consumption of medications known to affect protein metabolism (e.g., prescription-strength corticosteroids, non-steroidal anti-inflammatories, or acne medication) * Pregnancy * Allergy to dairy product or lactose intolerance * Fasting plasma glucose (FPG) ≥ 126 mg/dL * Oral glucose tolerance test (OGTT) ≥ 200 mg/dL