CompletedNot Applicable

Comparison of Intravenous Co-amoxiclav Versus Benzyl Penicillin

Pakistan310 participantsStarted 2018-01-01

Plain-language summary

To compare intravenous Co-amoxiclav versus Benzyl penicillin in children with severe streptococcal tonsillitis in terms of efficacy, safety and cost effectiveness.

Who can participate

Age range5 Years – 15 Years

SexALL

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Inclusion criteria

✓. Children who had 3 or 4 score according to Centor Criteria for tonsillitis/pharyngotonsillitis, were included in study
✓. Children between ages of 5 to 15 years
✓. Children with positive Rapid Antigen detection Test (RADT) for Streptococcus Pyogenes

Exclusion criteria

✕. Immunocompromised children
✕. Children with known hypersensitivity to Penicillins (esp Coamoxiclav and Benzyl penicillin)
✕. Children with liver or renal failure
✕. Children who were already using any oral or parenteral antibiotics

What they're measuring

treatment efficacy

Timeframe: 10 days

Trial details

NCT IDNCT04215770

SponsorCombined Military Hospital, Pakistan

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-11-01

View on ClinicalTrials.gov More Tonsillitis Streptococcal trials