Comparison of Esophageal Manometry and CT Scan Measurements (NCT04213911) | Clinical Trial Compass
WithdrawnNot Applicable
Comparison of Esophageal Manometry and CT Scan Measurements
Stopped: Lack of funding
United States0Started 2023-03
Plain-language summary
The goal of this study is to determine the relationship between esophageal pressure (Pes) and superimposed pressure (SP) in subjects with morbid obesity.
Who can participate
Age range18 Years – 99 Years
SexALL
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Inclusion Criteria:
* Patients who are scheduled to take a chest CT scan for the clinical purpose at MGH Radiology Department
* 6 adult subjects with BMI more than 40kg/m2
* 6 adult subjects with BMI less than 30kg/m2
* More than 18 years old
Exclusion Criteria:
* Presence of pneumothorax
* History of spontaneous pneumothorax
* Severe coagulopathy (INR ≥ 4)
* Severe thrombocytopenia (Platelets count ≤ 5,000/mm3)
* Usage of any devices with electric current generation such as pacemakers or internal cardiac defibrillator
* Recent esophageal trauma or surgery
* Other esophageal diseases, such as esophageal cancer, leak, varices, and hernia
* Presence of hypoxemia, short of breath and dysphagia.
* Presence or suspicion of pneumonia or lung fibrosis.
What they're measuring
1
Esophageal pressure measurement at a given superimposed pressure
Timeframe: through study completion, an average of 1 year