UnknownEarly Phase 1

Natural Killer Cells Infusion for Treating Acute Myeloid Leukemia Patients With Minimal Residual Disease

China6 participantsStarted 2020-01-01

Plain-language summary

This trial will evaluate the effectiveness and safety of haploid donor-derived in vitro activated natural killer(NK) cells infusion for Treating acute myeloid leukemia Patients With minimal residual disease.

Who can participate

Age range

1 Year – 80 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Patients diagnosed with acute myeloid leukemia;
. MRD after 2 course of standard chemotherapy;
. No plan for hematopoietic stem cell transplantation;
. Hemoglobin (Hb) \>=60g/L, white blood cell count (WBC) \>=2.5x10\^9/L, platelet count \>=30x10\^9/L;
. Patients have self-knowledge ability and can sign informed and voluntary consent forms;
. Patients or their clients, guardians of pediatric patients signed the informed and voluntary consent form and joined the study.

Exclusion criteria

. Intracranial hypertension or unconsciousness;
. Symptomatic heart failure or severe arrhythmia;
. Respiratory failure;
. With other types of malignant tumor diseases;
. T lymphocytic acute leukemia;

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Minimal Residual Disease (MRD)

Timeframe: 12 months

Trial details

NCT IDNCT04209712

SponsorShanghai iCELL Biotechnology Co., Ltd, Shanghai, China

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2020-12-31

Contact for this trial

Jiang ZHU

+86-15900398802 zhujiang@icell.com.cn

View on ClinicalTrials.gov More Acute Myeloid Leukemia trials