UnknownNot Applicable

The Effect of Regional Anaesthesia and Genetic Factors in the Development of Chronic Pain Following Total Knee Arthroplasty

Malta200 participantsStarted 2017-06-01

Plain-language summary

The study aims to assess the effect of spinal anaesthesia against a general anaesthesia with a femoral block, with respect to the incidence of chronic pain following a total knee replacement. It will also focus on genetic factors and their influence on chronic pain.

Who can participate

Age range18 Years – 75 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * patients able to undergo a total knee arthroplasty Exclusion Criteria: * age more than 75 years * known case of chronic pain syndromes * arthroplasty not due to osteoarthritis * sensitivity to any drugs used in protocol

What they're measuring

Pain Numerical Rating Scale on physiotherapy

Timeframe: 24 hours

WOMAC Score at 3 and at 6 months

Timeframe: 6 months

WOMAC Pain Score at 3 and at 6 months

Timeframe: 6 months

Trial details

NCT IDNCT04206046

SponsorSciberras, Stephen M.D.

Sponsor typeINDIV

Study typeINTERVENTIONAL

Primary completion2022-06-01

View on ClinicalTrials.gov More Arthroplasty, Replacement, Knee trials