Transcranial Direct Current Stimulation and Antisocial Behavior (NCT04204759) | Clinical Trial Compass
UnknownNot Applicable
Transcranial Direct Current Stimulation and Antisocial Behavior
Singapore101 participantsStarted 2019-11-03
Plain-language summary
The main objective of this study is to investigate the causal relationship between prefrontal cortex activity and antisocial behavior, as well as risk factors for antisocial behavior. Specifically, this study tests the hypothesis that upregulating activity in the prefrontal cortex through a non-invasive form of brain stimulation, transcranial direct current stimulation (tDCS) will reduce antisocial and aggressive behavior. The effects of 3 days of anodal stimulation over the prefrontal cortex are assessed.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Above 18 (with parental consent) or above 21 (without parental consent)
* Able to understand the nature of the study and give informed consent
Exclusion Criteria:
* History of or active neurologic, cardiovascular, or psychiatric disease including anxiety disorders (e.g., PTSD, panic attacks, obsessive-compulsive disorder) and mood disorders (e.g., depression)
* Currently consuming anti-convulsant, anti-psychotic, or sedative/hypnotic medications
* Currently consuming anti-depressants
* History of seizures
* Metallic implants on scalp
* Participated in any other non-invasive brain stimulation study in the same day
* Ever had an adverse reaction to tDCS
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Points in the Point Subtraction Aggression Paradigm after stimulation
Timeframe: Within 1 hour after the third consecutive active tDCS or sham session
2
Antisocial behavior inclinations after stimulation
Timeframe: Within 1 hour after the third consecutive active tDCS or sham session
3
Moral judgment ratings after stimulation
Timeframe: Within 1 hour after the third consecutive active tDCS or sham session
4
Delay discounting rates after stimulation
Timeframe: Within 1 hour after the third consecutive active tDCS or sham session
5
Helping behavior after stimulation
Timeframe: Within 1 hour after the third consecutive active tDCS or sham session
6
Antisocial behavior after stimulation
Timeframe: Within 1 hour after the third consecutive active tDCS or sham session