CompletedNot Applicable

Clinical Validation of Algorithms for Mean Systemic Filling Pressure and Automated Cardiac Output

Netherlands18 participantsStarted 2019-06-24

Plain-language summary

Prospective combined clinical validation of an algorithmic calculated mean systemic filling pressure (Pms-Nav) with the gold standard for Pms (Pms calculated from venous return curves during inspiratory hold procedures with incremental airway pressures; Pms-Insp). Secondary correlation between invasive cardiac output measurement versus 3D TOE and carotid echo doppler measured cardiac output.

Who can participate

Age range18 Years

SexALL

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Inclusion Criteria: * Good left and right ventricular ejection fraction * No significant valvular insufficiencies/stenoses * No significant comorbidity * Signed informed consent * Elective coronary artery bypass surgery * Postoperative mechanically ventilated admitted to the PACU Exclusion Criteria: * Withdrawal informed consent * History of pneumonectomy of lobectomy * Mechanical support of circulation * COPD Gold 3 or 4 * Complications during surgery * Postoperative bleeding \>50mL/15 minutes after admission to PACU - No thoracic drain in pleura * Postoperative pneumothorax * Participation in other research studies/trials * Elevated intra-abdominal surgery (\>12 mmHg)

What they're measuring

Clinical validation of Pms-algorithm

Timeframe: Hours

Trial details

NCT IDNCT04202432

SponsorCatharina Ziekenhuis Eindhoven

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2019-08-30

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