The Rate of Space Closure With Piezocision-based Corticotomy in Different Facial Types: A Split-m… (NCT04202016) | Clinical Trial Compass
CompletedNot Applicable
The Rate of Space Closure With Piezocision-based Corticotomy in Different Facial Types: A Split-mouth Design
Jordan23 participantsStarted 2018-11-01
Plain-language summary
23 female participants with class II div I will have extraction of bilateral first bicuspids 10 weeks after bond- up appointment. The extracted teeth will be preserved in special containers for subsequent microscopic analysis. Four months later, upon space closure phase, the patient will have a piezocision surgery on one side randomly chosen. Virtual models will be generated once before the surgery and monthly after for four and a half months. The models will be scanned by CADCAM and later tooth movement will be analyzed in regards to the rugae area.
Who can participate
Age range
15 Years – 29 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Young adults and adults (15-29).
* Middleastern Caucasian.
* Females.
* Having the defined orthodontic appliance, slot size, prescription, and technique of space closure.
* Class II division I of moderate space requirement that is planned to have the first premolar extracted.
* Average or high facial type.
* Healthy patients without systematic diseases that could affect bone and tooth movement and no contraindication (medical or psychological) to avoid oral surgery.
* No active periodontal diseases as this effect the cytokines expression (stabilized prostaglandin (PG) health)
* Good oral hygiene.
* No other method of non-surgical acceleration technique to be used.
Exclusion Criteria:
* Patients who refused to consent for the study.
* The two extremes of age (younger than 14 and older than 29).
* Having other than the defined orthodontic appliance, slot size, prescription, and technique of space closure.
* Extraction cases of high space requirements or other teeth than the first premolar.
* Patients with systematic diseases that could affect bone and tooth movement and no contraindication (medical or psychological) avoid oral surgery.
* Active periodontal diseases.
* Other methods of non-surgical acceleration technique to be used.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Rate of space closure
Timeframe: four and half months
Trial details
NCT IDNCT04202016
SponsorJordan University of Science and Technology