CompletedNot Applicable

Dietary Monosaccharide Supplementation in Patients With Congenital Disorders of Glycosylation

United States20 participantsStarted 2018-12-06

Plain-language summary

Researchers are trying to assess whether the use of simple sugars given as a daily dietary supplement can improve the health of children with congenital disorders of glycosylation (CDG).

Who can participate

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patient has a biochemically and genetically proven congenital disorder of glycosylation * Patient is receiving (or planning to receive) oral simple sugar supplementation Exclusion Criteria: * Aldolase B deficiency * Galactosemia * Hemolytic uremic syndrome * Severe anemia * Galactose intolerance

What they're measuring

Measuring effects of oral monosaccharide supplements through growth measurements

Timeframe: length of study, up to 2 years

Measuring effects of oral monosaccharide supplements through blood sugar levels

Timeframe: length of study, up to 2 years

Measuring effects of oral monosaccharide supplements through liver function results

Timeframe: length of study, up to 2 years

Measuring effects of oral monosaccharide supplements through coagulation results

Timeframe: length of study, up to 2 years

Trial details

NCT IDNCT04198987

SponsorMayo Clinic

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-06-11

View on ClinicalTrials.gov More Congenital Disorder of Glycosylation trials