CompletedNot Applicable

Listening to Mom 2: Neural, Clinical and Language Outcomes

United States57 participantsStarted 2019-11-25

Plain-language summary

The purpose of this study is to examine whether playing recordings of a mother's voice to her infant while in the hospital nursery is an effective treatment for promoting healthy brain and language development in infants born preterm.

Who can participate

Age range24 Weeks – 31 Weeks

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Infants born preterm at Stanford Children's Hospital between 24 0/7 - 31 6/7 weeks gestational age Exclusion Criteria: * Congenital anomalies * Recognizable malformation syndromes * Active seizure disorders * History of Central Nervous System infections * Hydrocephalus * Major sensori-neural hearing loss * Likelihood to be transferred from NICU to alternate care facility or home environment prior to 36 weeks PMA and/or brain MRI scan * Intraventricular Hemorrhage Grades III-IV * Cystic periventricular leukomalacia (PVL) * Surgical treatment for necrotizing enterocolitis * Small for gestational age (SGA) \<3 percentile and/or Intra-uterine growth restriction (IUGR) no head sparing * Twin-to-twin transfusions

What they're measuring

Standard and Raw Scores of Receptive and Expressive Language on MacArthur-Bates Communicative Development Inventory (CDI): Words and Sentences

Timeframe: 18 month follow-up adjusted age for preterm birth

Trial details

NCT IDNCT04193579

SponsorStanford University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-04-26

View on ClinicalTrials.gov More Premature Birth trials