CompletedNot Applicable

Evaluating the Utility of Continuous Positive Airway Pressure in the Treatment of High Altitude Pulmonary Edema

United States64 participantsStarted 2020-01-20

Plain-language summary

The primary objective is to evaluate the efficacy of continuous positive pressure on resolution of high-altitude pulmonary edema vs high flow oxygen. The secondary objective is to derive an incidence of high-altitude pulmonary edema based on the elevation and timing from which the subject arrives. Additionally, in a convenience sample of the base study population, an ultrasound evaluation for the presence of B lines in the lungs will be conducted after 2 hours.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Male or female, age 18 years or greater * Oxygen saturation below 85% * Recent arrival to high altitude * Dyspnea and cough * Xray revealing non-cardiogenic pulmonary edema Exclusion Criteria: * Pregnancy * Age below 18 * Patients with respiratory failure requiring intubation * Patients with altered mental status * Patients with impaired decision-making capacity * Patients with a history of congestive heart failure, CAD, COPD, asthma, known current pneumonia * Extreme facial hair precluding application of CPAP

What they're measuring

Time to resolution of HAPE

Timeframe: 2 hours

Trial details

NCT IDNCT04186598

SponsorCommonSpirit Health

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-09-13

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