People who suffer from binge eating disorder experience recurrent episodes of binge eating.During these episodes, they consume an unusually large amount of food in a short amount of time and experience loss of control over eating. However, why such binge eating episodes occur is still largely unknown. This makes it difficult to develop targeted treatments. In this project, the experimenters are investigating the brain mechanisms that give rise to the disorder. They hypothesize that the binge eating episodes are due to an increased variability in reward processing, which they will assess repeatedly over days. They will test this hypothesis using mathematical models based on behavioural and MRI measurements that are related to the processing of rewards.
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Variability in blood-oxygen-level dependent (BOLD) signalling in the NAcc during effort allocation task
Timeframe: 100 min
Trial-to-trial variability in reward seeking in an effort allocation task
Timeframe: 40 min
Variability in BOLD signalling in the NAcc for food-cue reactivity
Timeframe: 15