Intermittent episodes of hypoxemia and/or bradycardia, also defined as cardio-respiratory events (CRE) are very frequent in preterm infants and may result in transient hypoxia and hypoperfusion of target organs, with possible clinical implications. The hemodynamic instability that characterizes the first 72 hours of life, also called as transitional period, place preterm infants at high risk of complications and may contribute to enhance fluctuations in end-organ perfusion and oxygenation induced by CRE. In this study we aimed to explore cardiovascular and cerebrovascular changes determined by different CRE types in preterm infants during the transitional period.
Age range
1 Day – 3 Days
Sex
ALL
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Increase/reduction of cTOI during isolated desaturation, isolated bradycardia and desaturation-bradycardia
Timeframe: 0-72 hours of life
Increase/reduction of cFTOE during isolated desaturation, isolated bradycardia and desaturation-bradycardia
Timeframe: 0-72 hours of life
Increase/reduction of cTHI during isolated desaturation, isolated bradycardia and desaturation-bradycardia
Timeframe: 0-72 hours of life
Increase/reduction of CO during isolated desaturation, isolated bradycardia and desaturation-bradycardia
Timeframe: 0-72 hours of life72 hours
Increase/reduction of SV during isolated desaturation, isolated bradycardia and desaturation-bradycardia
Timeframe: 0-72 hours of life
Increase/reduction of ICON during isolated desaturation, isolated bradycardia and desaturation-bradycardia
Timeframe: 0-72 hours of life
Increase/reduction of SVR during isolated desaturation, isolated bradycardia and desaturation-bradycardia
Timeframe: 0-72 hours of life