Measuring the Cardio-metabolic Response to Diet Quality Modification During Night Work. (NCT04182867) | Clinical Trial Compass
TerminatedNot Applicable
Measuring the Cardio-metabolic Response to Diet Quality Modification During Night Work.
Stopped: Participant recruitment difficulties within the time frame
United Kingdom4 participantsStarted 2021-05-28
Plain-language summary
The aim of this pilot study is to investigate the acute impact of diet quality modification during night work on 24-hr glucose variability (GV) and heart rate variability (HRV) in healthy free-living employees.
Who can participate
Age range18 Years – 60 Years
SexALL
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Inclusion Criteria:
* Current night shift worker (defined as a period of work between 11pm and 6am) working regular blocks of 3 night shifts.
* Body mass index between 18.5 and 35 kg/m2.
* Weight stable (no weight change by more than 3 kg in the last 2 months).
* Not a regular smoker (1 or more cigarettes per day) and would be willing not to smoke for the duration of the study.
* Not pregnant or breastfeeding.
* Not diagnosed with heart attack, stroke, angina, thrombosis, liver or kidney diseases, diabetes, chronic gastrointestinal disorder or cancer.
* Not currently taking medication to stabilize blood glucose (e.g. acarbose, metformin or sulfonylureas).
* Not started new medication within the last 3 months likely to interfere with energy metabolism, appetite regulation and hormonal balance, including: anti-inflammatory drugs or steroids, antibiotics, androgens, phenytoin, erythromycin or thyroid hormones.
* Do not take medication for blood pressure e.g. diuretics, (beta-blockers, Ca-channel, ACE inhibitors, Angiotensin Receptor blockers)
* Do not have diagnosed hypertension (high blood pressure, systolic blood pressure that is higher than 180 mmHg and or diastolic blood pressure that is higher than 110 mmHg).
* Not diagnosed with arterial fibrillation or any other condition that affects heart rate (e.g. arrhythmia).
* No food intolerance, allergies, hypersensitivity or follow any dietary restrictions (e.g. gluten intolerance, coeliac, lactose intolerance, vegan or vegetari…
What they're measuring
1
Blood glucose variability (mean amplitude of glycaemic excursions)