Triggers And Risk Factors to Develop a Reversible Cerebral Vasoconstriction Syndrome (NCT04179383) | Clinical Trial Compass
UnknownNot Applicable
Triggers And Risk Factors to Develop a Reversible Cerebral Vasoconstriction Syndrome
France225 participantsStarted 2019-12-05
Plain-language summary
This study will be the first to evaluate the role played by potential precipitating factors and risk factors in Reversible Cerebral Vasoconstriction Syndrome (RCVS) through of prospective selection of carefully characterised patients and controls. The impact of these factors on the prognosis will be evaluated through a follow-up assessment of patients.
Our study will include the formation of a clinicoradiological database and a biobank (plasma, cerebro-spinal fluid, DNA) which will be the tools of a future large multicentre study on RCVS.
Who can participate
Age range
18 Years – 100 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria:
* For the Patients
* Men and women of 18 and more years old
* Taken care in the CHU of Montpellier
* Diagnosis of SVCR or SVCR without visible vasoconstriction makes in 14 days preceding the inclusion
* According to the consensual criteria of diagnosis and those of the international classification of the headaches ICHD-3
* Informed consent and writes for the participation in the study
* For volunteers
* Men and women of 18 and more, mated in the Cases on the sex and the age
* Patients with an acute pathology not Neurological and not vascular (for example, eye foreign body) OR Healthy Subjects
* Informed written consent and for the participation in the study
Exclusion criteria:
* Coma, insanity, language barrier or severe aphasia preventing from answering the questions
* Follow-up considered impossible for 3 months (e.g.: priority associated pathology in the care, the transfer(transformation))
* People placed under legal protection
* Refusal to participate in the study
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Presence of, at least, one assumed trigger or risk factors