UnknownNot Applicable

Örebro Multicenter Study on Operative Treatment of Cervical Radiculopathy

Sweden110 participantsStarted 2020-01-20

Plain-language summary

This study compares anterior cervical decompression and fusion (ACDF) to posterior foraminotomy (PF) in surgical treatment for cervical radiculopathy (CR) caused by root canal compression, in a multicenter prospective randomized trial. The investigators hypothesize equal decompression of nerve root, and equal clinical outcome in both treatment groups.

Who can participate

Age range18 Years – 65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Symptoms of radiating arm pain with duration of at least six weeks * Neck disability index (NDI) over 30 points (60%); * Correlating findings on MRI on one or two cervical levels * Eligible for both treatments * Ability to understand and read Swedish. Exclusion Criteria: * Previous cervical spine surgery * More then two cervical levels requiring treatment * Severe facet joint osteoarthritis * Symptoms or marked radiologic signs of myelopathy * Drug abuse * Dementia or expected low compliance * Cervical malformation * Marked instability, 3.5-mm translation or \>11 degrees more motion compared to adjacent segments * History of severe cervical trauma * Generalized pain syndrome or WAD * Pregnancy * Rheumatoid arthritis * Ankylosing spondylitis * Malignancy * Active infection or another severe systemic disease * Patients that are unsuitable for either intervention deemed by the consultant spine surgeon

What they're measuring

Neck Disability index, NDI.

Timeframe: 4-6 weeks, 3 months, 1 year, 2 year, 5 year

Trial details

NCT IDNCT04177849

SponsorRegion Örebro County

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-01

Contact for this trial

Marek Holy, MD

+46 0196025323 marek.holy@regionorebrolan.se