CompletedPhase 4

The Use of Intra-articular Corticosteroid Injection to Treat Osteoarthritis of the Carpometacarpal Joint

Canada61 participantsStarted 2020-12-02

Plain-language summary

This randomized clinical trial (RCT) will evaluate 6-month outcomes following intra-articular injections for arthritis of the thumb carpometacarpal (CMC) joint by comparing corticosteroid plus local anesthetic versus saline (placebo) plus local anesthetic.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Participants must be 18 years old or older at recruitment * Present clinical and radiographic signs of thumb CMC OA using the American College of Rheumatology (ACR) criteria for the classification of hand osteoarthritis. Exclusion Criteria: * History of inflammatory arthritis * Previous steroid joint injection to either thumb CMC joint * Pregnancy or breastfeeding * Psychiatric illness * Cognitive impairment, or health conditions that preclude informed consent or receiving the injection * People who do not speak/read/understand English, have no fixed address or contact, or are unwilling to complete follow-ups

What they're measuring

Change in Pain with movement

Timeframe: baseline, 6 weeks, 3 months, 6 months

Trial details

NCT IDNCT04177433

SponsorUniversity of Alberta

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-09-29

View on ClinicalTrials.gov More Osteoarthritis of the Carpometacarpal Joint trials