CompletedNot Applicable

Confocal Laser Endomicrospy in Colonic Diverticular Disease

Ecuador63 participantsStarted 2019-11-01

Plain-language summary

Confocal laser endomicroscopy detects inflammatory markers undetectable during high definition endoscopy. The investigators aimed to evaluate the role of peridiverticular and colonic mucosa inflammation in the prediction of the complicated diverticular disease using confocal laser endomicroscopy evaluation in the peridiverticular area in consecutive patients.

Who can participate

Age range

18 Years – 80 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Above 18 years old * Writeen informed consent provided. * Endoscopic visualization of diverticular disease during colonoscopy. * Adequate bowel preparation BBPS \>2 in each colon segment Exclusion Criteria: * Under 18 years old. * Refuse to sign written informed consent. * Pregnancy or nursing. * Previous colorectal surgery * History of colorectal cancer * Known allergy to fluorscein * Uncontrolled coagulopathy * History of complicated diverticular disease * Patients with inflammatory bowel disease * Patients with severe comorbidities: kidney and liver failure * NSAIDs and antibiotics two weeks prior enrollment * Historyh of alcohol or drug abuse * Patients with severe mental illness * Patients with incomplete evaluation of the colon

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

ocurrence of complicated diverticular disease

Timeframe: up to 12 months

ocurrence of complicated diverticular disease

Timeframe: up to 24 months

Trial details

NCT IDNCT04173182

SponsorInstituto Ecuatoriano de Enfermedades Digestivas

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2021-02-01

View on ClinicalTrials.gov More Diverticular Disease trials