CompletedNot Applicable

Confocal Laser Endomicrospy in Colonic Diverticular Disease

Ecuador63 participantsStarted 2019-11-01

Plain-language summary

Confocal laser endomicroscopy detects inflammatory markers undetectable during high definition endoscopy. The investigators aimed to evaluate the role of peridiverticular and colonic mucosa inflammation in the prediction of the complicated diverticular disease using confocal laser endomicroscopy evaluation in the peridiverticular area in consecutive patients.

Who can participate

Age range18 Years – 80 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Above 18 years old * Writeen informed consent provided. * Endoscopic visualization of diverticular disease during colonoscopy. * Adequate bowel preparation BBPS \>2 in each colon segment Exclusion Criteria: * Under 18 years old. * Refuse to sign written informed consent. * Pregnancy or nursing. * Previous colorectal surgery * History of colorectal cancer * Known allergy to fluorscein * Uncontrolled coagulopathy * History of complicated diverticular disease * Patients with inflammatory bowel disease * Patients with severe comorbidities: kidney and liver failure * NSAIDs and antibiotics two weeks prior enrollment * Historyh of alcohol or drug abuse * Patients with severe mental illness * Patients with incomplete evaluation of the colon

What they're measuring

ocurrence of complicated diverticular disease

Timeframe: up to 12 months

ocurrence of complicated diverticular disease

Timeframe: up to 24 months

Trial details

NCT IDNCT04173182

SponsorInstituto Ecuatoriano de Enfermedades Digestivas

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2021-02-01

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