CompletedEarly Phase 1

PET and MRI Imaging of Brain Tumors Using [18F]PARPi

United States5 participantsStarted 2019-11-01

Plain-language summary

This study is to collect data about how 18FPARPi can be used together with PET/positron emission tomography and MRI/magnetic resonance imaging scans to take pictures of brain cancer

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients with new or suspected recurrent brain tumors (including suspected recurrent brain tumors showing growth from any preceding scan) * Age \>/= 18 years * Minimum at least one brain lesion size \>/= 1.5cm diameter * Scheduled to undergo treatment at MSK * Willingness to sign informed consent * Able to receive intravenous gadolinium contrast per MSK Department of Radiology guidelines Exclusion Criteria: * Any contraindication to 3T MRI (PET/MR scanner is 4.0 Tesla) * Pregnancy or breast-feeding women

What they're measuring

SUVmax measurements

Timeframe: Up to 24 weeks

Trial details

NCT IDNCT04173104

SponsorMemorial Sloan Kettering Cancer Center

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-02-05

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