A Study of Erdafitinib Versus Investigator Choice of Intravesical Chemotherapy in Participants Who Received Bacillus Calmette-Guérin (BCG) and Recurred With High Risk Non-Muscle-Invasive Bladder Cancer (NMIBC)

Inclusion Criteria: * Histologically confirmed, recurrent, non-muscle-invasive urothelial carcinoma of the bladder. Variant pathology are allowed * Tumor with specified fibroblast growth factor receptor (FGFR) mutations or fusions * Bacillus Calmette- Guerin (BCG)-unresponsive after adequate BCG therapy or BCG experienced participants * Refuses or is not eligible for cystectomy (Cohort 1 and Cohort 2 only) * Eastern Cooperative Oncology Group (ECOG) performance status Grade 0-1 * Must sign an informed consent form (ICF) (or their legally acceptable representative must sign) indicating that he or she understands the purpose of, and procedures required for, the study and is willing to participate in the study * A woman of childbearing potential must have a negative pregnancy test (beta-human chorionic gonadotropin \[beta-hCG\]) (urine or serum) within 7 days before randomization (Cohort 1) or the first dose of study drug (Cohort 2 and Cohort 3) * Adequate bone marrow, liver, and renal function as specified in the protocol Exclusion Criteria: * Histologically confirmed, muscle-invasive (T2 or higher stage) urothelial carcinoma of the bladder * Histopathology demonstrating any small cell component, pure adenocarcinoma, pure squamous cell carcinoma, or pure squamous CIS of the bladder * Prior treatment with an FGFR inhibitor * Active malignancies other than the disease being treated under study. The only allowed exceptions are: (a) skin cancer treated within the last 24 months …