This study evaluates the influence of the transversus abdominis plane block on the intensity of postoperative pain and the concentration of proinflammatory and pain factors after hysterectomy by laparotomy. The patients will be randomized in three groups.In the first group, patients will receive intravenous, systemic, multimodal analgesia.In the second group there will be patients in who will be given the TAP block. The TAP block will be given postoperatively before waking. It will be given bilaterally in the before mentioned anatomic region (the so-called lateral TAP block). In the third group there will be patients who will be treated with TAP block in addition to systemic, mutimodal analgesia. The research will be based on completing a questionnaire (VAS scale and QoR questionnaire) and taking peripheral blood out. We expect that the concentration of proinflammatory and pain factors in patients treated with a TAP block will be lower and the quality of recovery will be better than that of patients receiving standard analgesic therapy (systemic multimodal analgesia).
Age range
18 Years
Sex
FEMALE
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The impact of three forms of postoperative analgesia (TAP block, systemic multimodal analgesia, combined TAP block and systemic multimodal analgesia)on postoperative pain after gynecological surgery
Timeframe: 48 hours
Concentration of proinflammatory and pain factors in patients on postoperative pain after gynecological surgery
Timeframe: Before surgery and 6, 24 and 48 hours after surgery
Quality of recovery after gynecological surgery
Timeframe: 30 days