Retrospective Cohort Study of the Effectiveness of the Prophylactic Vaccine Against the Human Papilloma Virus in the Prevention of Recurrence in Women Who Have Received an Excisional Therapy by HSIL / CIN.

Plain-language summary

A retrospective cohort study of women treated by excisional therapy due to HSIL/ CIN at Clínico San Carlos Hospital between 2012-2018. The effectiveness of prophylactic vaccination against HPV in women treated for HPV-related disease will be evaluated. For this purpose, the percentage of cervical lesion recurrence among a group of treated and vaccinated women against HPV between the years 2015-2018 will be compared with a control group of treated and non-vaccinated women against HPV since 2012-2015. It will be an essential requirement that the patient provide a vaccination card from their health center where there is proof of their immunization status and date of administration. Inclusion criteria: * Women older than 18 years who received excisional therapy due to HSIL /CIN injury confirmed histologically. * Women who sign informed consent. * Patients with negative results in the first post-surgery control. * Patients who have received HPV vaccination and provide vaccination card. Exclusion criteria: * Women who do not wish or cannot give their informed consent and / or do not comply with the requirements of the study. * Patients treated by an indication other than HSIL/CIN. * Patients under immunosuppression conditions.

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