CRESPI - Respiratory Health of Children in Daycare (NCT04170881) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
CRESPI - Respiratory Health of Children in Daycare
France2,000 participantsStarted 2019-12-03
Plain-language summary
CRESPI - RESPIratory health of Children in daycare
The CRESPI study, will be a cohort of 1500/2000 children attending daycare in Paris region, and will be initiated in November 2019.
The aim of the project is to study the impact of environmental exposures to cleaning products and disinfectants on respiratory health of infants and toddlers (\< 3 years) in daycares
Two specific aims were defined:
1. evaluate environmental exposure to cleaning products by complementary and innovative tools: air quality measurements in daycares, specific standardized questionnaire, identification of compounds of the products via a database and a Smartphone application to scan bar codes and inform on product use
2. evaluate the impact of early exposure in daycares and at home on respiratory health of young children
Who can participate
Age range
2 Months – 4 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
Children :
* aged from 2 months to 3 years (\< 4 years) attending daycares in Paris region, among those which accepted to participate to the CRESPI study
* signed and dated written informed consent form obtained from at least one parent
Nursery workers :
* all those who accepted to participate
* signed and dated written informed consent form obtained
Exclusion Criteria:
Children and workers : if it is impossible for them (parents or workers) to understand French langage and/or to follow the questionnaire of the study
Children
* both parents less than 18 years old
* parents subjected to a legal protection measure or deprived of liberty by judicial or administrative decision
* if at least two children of the same familly attended the same daycare, only the youngest one will be included. In case of twins or triplets, only one children will be chosen at random.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Current wheezing
Timeframe: at inclusion (2019-2021)
2
Longitudinal wheezing
Timeframe: at inclusion (2019-2021), every month by a smartphone application (during 1 year after inclusion), every 6 months by questionnaires (2021 to 2023)
Trial details
NCT IDNCT04170881
SponsorInstitut National de la Santé Et de la Recherche Médicale, France