CompletedNot Applicable

Simultaneously PET/MRI in Prolonged DOC Patients

China24 participantsStarted 2018-01-01

Plain-language summary

Recently introduced hybrid PET/MR scanners provide the opportunity to measure simultaneously, and in direct spatial correspondence, both metabolic demand and functional activity of the brain, hence capturing complementary information on the brain's physiological state. Here we exploited PET/MR simultaneous imaging to explore the relationship between the metabolic information provided by resting-state fluorodeoxyglucose-PET (FDG-PET) and fMRI (rs-fMRI) in patients with disorders of consciousness.

Who can participate

Age range16 Years – 80 Years

SexALL

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Inclusion Criteria: * DOC patients （acute, subacute or chronic period）: Coma, UWS and MCS. Exclusion Criteria: * neuromuscular blocking agents or sedative drugs administered within the prior 24 hours； * unstable medical condition； * mental implant in the brain

What they're measuring

resting-state fMRI

Timeframe: Within 7 days

fludeoxyglucose (FDG-)PET

Timeframe: Within 7 days

Trial details

NCT IDNCT04164680

SponsorHangzhou Normal University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2021-01-01

View on ClinicalTrials.gov More Disorder of Consciousness trials