Cervical Stiffness Measurement in Cervical Insufficiency
United States136 participantsStarted 2020-01-15
Plain-language summary
The goal of this cross sectional study is to evaluate the differences in cervical stiffness between patients who present for cerclage placement versus normal pregnancies.
The central hypothesis is that women for whom a cerclage is indicated will have cervical stiffness measurements lower than normal controls. Cervical stiffness will be objectively measured by the closing pressure Pcl using the Pregnolia measurement device. This is performed during a speculum exam by placing the measurement probe on the ectocervix.
In current clinical care, there is no objective measurement of cervical stiffness. An accurate measurement of cervical stiffness that correlates with clinical outcome will advance the field. Successful completion of the current study will spark future studies that correlate cervical stiffness pcl in a prospective study.
Who can participate
Age range18 Years
SexFEMALE
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Inclusion criteria
✓. Pregnant women over 18 years of age.
✓. Singleton gestation.
✓. Gestational ages between 12w0d and 22w6d.
✓. Candidates for cerclage
✓. Normal controls, which will be matched to cerclage subjects by gestational age and parity