Acupuncture has been a means of treating headaches and migraine since 2002 and is now a World Health Organisation-recognized prophylactic treatment for migraine. Brain activation/de-activation via acupuncture modifies the haemodynamic responses in the brain which may impact the sensorial, cognitive and affective dimensions of pain. Randomized studies on patients suffering from aura-free migraine have shown that the painkilling effect of regular acupuncture sessions on the cerebral substratum, compared with simulated sham-type acupuncture, can reduce the frequency of bouts of migraine, number of days with headaches and also their intensity. Modifications to the white matter (WM) and grey matter (GM) occur after repeated sessions of acupuncture treatment for pain and these are observable via magnetic resonance imaging (MRI). It is a very sensitive technique and often used to detect functional and structural brain changes.
Age range
18 Years – 60 Years
Sex
ALL
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A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Regional homogeneity map in Interventional group patients BEFORE first real acupuncture session.
Timeframe: At the inclusion visit (Vinc) on Day 0 - Start of therapy
Regional homogeneity map in Interventional group patients AFTER first real acupuncture session.
Timeframe: At the inclusion visit (Vinc) on Day 0 - Start of therapy
Regional homogeneity map in Placebo group patients BEFORE first real acupuncture session.
Timeframe: At the inclusion visit (Vinc) on Day 0 - Start of therapy
Regional homogeneity map in Placebo group patients AFTER first real acupuncture session.
Timeframe: At the inclusion visit (Vinc) on Day 0 - Start of therapy
Regional homogeneity map in Interventional group patients BEFORE last real acupuncure session
Timeframe: Sixty days after inclusion in the trial (Day 60) - end of therapy
Regional homogeneity map in Interventional group patients AFTER last real acupuncure session
Timeframe: Sixty days after inclusion in the trial (Day 60) - end of therapy
Regional homogeneity map of Placebo group patients BEFORE last placebo acupuncture session
Timeframe: Sixty days after inclusion in the trial (Day 60) - end of therapy
Regional homogeneity map of Placebo group patients AFTER last placebo acupuncture session
Timeframe: Sixty days after inclusion in the trial (Day 60) - end of therapy