TerminatedNot Applicable

Hyperprolactinemia and Adrenal Steroidogenesis

Stopped: Preliminary analyses of the samples provide no indication for a clinically relevant relationship between hyperprolactinemia and stimulation of adrenal steroidogenesis.

Switzerland5 participantsStarted 2021-06-24

Plain-language summary

The purpose of this study is to explore the effects of prolactin on adrenal steroid profiles in patients with hyperprolactinemia due to prolactinomas before and after initialisation of treatment.

Who can participate

Age range18 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Aged 18 years or older * Female and pre-menopausal * Serum prolactin \> 150 ng/ml Exclusion Criteria: * Corticotropic and/or thyreotropic insufficiency * Pregnancy, planned pregnancy or breastfeeding * Physical or psychological condition likely to interfere with the normal conduct of the study and interpretation of the study results as judged by the investigator * Incapacity to give informed consent

What they're measuring

Covariation of plasma prolactin and plasma dehydroepiandrosterone

Timeframe: From pre-treatment till 5 weeks of treatment

Trial details

NCT IDNCT04146389

SponsorInsel Gruppe AG, University Hospital Bern

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2023-11-06

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