CompletedNot Applicable

Angiographic Control Vs. Ischemia-driven Management of Patients Treated with PCI on Left Main with Drug-eluting Stents

Italy606 participantsStarted 2019-10-11

Plain-language summary

The present study aims to compare a planned angiographic control (PAC) follow-up strategy vs. conservative management for patients treated with drug-eluting stents on unprotected left main artery in a prospective, randomized setting. PAC will be performed by coronary computed tomography (CCT), to avoid the limitations of the invasive coronary angiography which is usually employed to perform PAC. The superiority of a PAC-based approach will be tested on a hard clinical end-point such as the incidence of major adverse cardiovascular events. The investigators will also assess the performance of CCT as a tool to perform PAC.

Who can participate

Age range18 Years – 85 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: Patients with ULM disease treated by PCI with DES-II with the following inclusion criteria: * Age 18-85. * Glomerular filtration rate \> 30 ml/min Indication to percutaneous revascularization of ULM according to Syntax score (\< 33) or, in dubious cases, after Heart Team evaluation Exclusion Criteria: * Cardiogenic shock * Refusal or inability to provide informed consent

What they're measuring

Major adverse cardiovascular events (MACE)

Timeframe: 18 months after the index revascularization

Trial details

NCT IDNCT04144881

SponsorA.O.U. Città della Salute e della Scienza

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-09-03

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