UnknownNot Applicable

Effects of Short-term Therapeutic Fasting on Nausea and Vomiting Due to Chemotherapy

France30 participantsStarted 2022-01-20

Plain-language summary

This study aims to estimate the effect of the practice of a short-term partial fasting compared to a usual alimentation on nausea and vomiting within 5 days after the start of a chemotherapy session on 2 successive chemotherapy courses (4 sessions of chemotherapy) in patients starting treatment with highly emetogenic chemotherapy (ABVD or AVD protocol).

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * patient starting a treatment by chemotherapy ABVD or AVD * patient affiliated to a social security scheme * patient who gives his informed consent before any procedure related to the study Exclusion Criteria: * patient with diabetes * patient with recent gastric ulcer * patient with low BMI (less than 18,5 for patients under 70 or less than 21 for patient over 70) * albuminemia \<35 * patient wiht loss weight \> 10% in 6 months * pregnant or lactating women * chronic alcoholism * unable to understand the objectives and risks of the study * patient with psychiatric desorder, under guardianship or under judicial protection * patient who cannot read

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

nausea and vomiting evaluation and quantification

Timeframe: Day 1 (first day of the chemotherapy cycle),

nausea and vomiting evaluation and quantification

Timeframe: day 2 of the chemotherapy cycle

nausea and vomiting evaluation and quantification

Timeframe: day 3 of the chemotherapy cycle

nausea and vomiting evaluation and quantification

Timeframe: day 4 of the chemotherapy cycle

nausea and vomiting evaluation and quantification

Timeframe: day 5 of the chemotherapy cycle

Trial details

NCT IDNCT04141514

SponsorCentre Hospitalier Universitaire de la Réunion

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-11-19

Contact for this trial

Mélanie BEGORRE

+262 (0)262 90 78 85 melanie.begorre@chu-reunion.fr

View on ClinicalTrials.gov More Nausea Post Chemotherapy trials

Plain-language summary

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

nausea and vomiting evaluation and quantification

Timeframe: Day 1 (first day of the chemotherapy cycle),

nausea and vomiting evaluation and quantification

Timeframe: day 2 of the chemotherapy cycle

nausea and vomiting evaluation and quantification

Timeframe: day 3 of the chemotherapy cycle

nausea and vomiting evaluation and quantification

Timeframe: day 4 of the chemotherapy cycle

nausea and vomiting evaluation and quantification

Timeframe: day 5 of the chemotherapy cycle