This study is designed to assess the therapeutic effect that music creativity engagement has on cognition and social/emotional well-being, with a special interest in quantifying the associated connectivity changes in the brain. Investigators will measure the effect that a creative music intervention has on health-related outcomes for mild cognitive impairment (MCI) patients using novel neural markers, laboratory-based cognitive tasks, assessments of loneliness, perceptions of stress, and social support.
Age range
18 Years – 90 Years
Sex
ALL
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Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Change from baseline in functional resting state brain activity at follow-up visit.
Timeframe: Functional magnetic resonance imaging will be obtained at enrollment and within one month since the completion of the music course.
Mean change from baseline in level of creativity using scores on Guilford's alternative Uses Divergent Thinking Test
Timeframe: Creativity will be measured at enrollment and within one month since the completion of the music course.
Mean change in scores from baseline in perceived social support subscales of the Medical Outcomes Studies, including emotional support, tangible support, affectionate support, and positive social interactions.
Timeframe: Creativity will be measured at enrollment and within one month since the completion of the music course.
Mean change from baseline in quality of life scores each subscale of the SF-36
Timeframe: Quality of life will be measured at enrollment and within one month since the completion of the music course.
Mean change from baseline in inhibition and inhibition/switching trials on the color-word interference test of the Delis Kaplan Executive Function System (DKEFS)
Timeframe: Cognitive scores will be measured at enrollment and within one month since the completion of the music course.
Mean change from baseline in cognitive scores (digit span forward, digit span backward, digit span sequencing, and total raw score) on the digit span test of the Wechsler Adult Intelligence Scale (WAIS).
Timeframe: Cognitive scores will be measured at enrollment and within one month since the completion of the music course.
Mean change from baseline in perseverative errors on the Wisconsin Card Sorting Test (WCST)
Timeframe: Cognitive scores will be measured at enrollment and within one month since the completion of the music course.
Mean change from baseline in affect scores on the Positive and Negative Affect Scale
Timeframe: Daily affect scores will be measured for 7 days after enrollment and 7 days after the final follow-up visit that will take place within 1 month after the completion of the music course.
Mean change from baseline in emotion regulation scores on the Emotional Regulation Scale
Timeframe: Emotion regulation scores will be measured at enrollment and at the follow-up visit that will take place within one month after the completion of the music course.