CompletedNot Applicable

Hypoalbuminemia in Mild Acute Stroke and Cognitive Impariment Post-stroke

China435 participantsStarted 2017-01-01

Plain-language summary

This registration enrolled patients with acute ischemic stroke within 72 hours after stroke ictus. Patients was identified as first-ever stroke based on past medical histrory. Admission CT was conducted to exclude hemorrhagic stroke, but not those bleeding transformation after ischemia injury. Baseline characteristics, including demographics, vascular risk factors, lab tests and neuroimagings were collected. Patients were followed up for cognitive assessments.

Who can participate

Age range40 Years – 80 Years

SexALL

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Inclusion criteria

✓. acute first-ever ischemic stroke and admitted within 72 hours after onset;
✓. clinical stroke diagnosis was confirmed with positive diffusion-weighted magnetic resonance imaging (DW-MRI), those with isolated posterior circulations infarcts were exclude ;
✓. presented with mild stroke severity ( admission NIHSS score ≤5);
✓. age between 40 and 80 years.

Exclusion criteria

✕. Patients with index cognitive impairment or under current anti-dementia or psychiatric medication;
✕. patients with large infarcts (≥1/3 middle cerebral artery territory);
✕. patients with severe language or physical disability that impede neuropsychological testing;
✕. patients with recurrent transient ischemic attack (TIA)/stroke during follow-up;
✕. coexisting serious conditions known to impair cognitive function

What they're measuring

PSCI

Timeframe: 6 months post-stroke

Trial details

NCT IDNCT04135872

SponsorDongguan People's Hospital

Sponsor typeOTHER_GOV

Study typeOBSERVATIONAL

Primary completion2018-06-30

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