WithdrawnNot Applicable

Regional Anesthesia to Relief Zoster Pain

Stopped: No enrollement and covid

Vietnam0Started 2020-05-15

Plain-language summary

Pain in Herpes is a serious issue for patients. at the acute phase it is a moderate to severe pain . 30% patients will develop a post herpetic neuralgia this percentage up to 70 % after 60 years old. this post herpetic neuralgia will affect their life. Publication showed the efficiency of regional anesthesia on pain at the acute phase and a recent meta-analysis showed the role of efficient pain relief on the prevention of post herpetic neuralgia. there are still 2 questions to answer: 1/ do we need to perform the regional anesthesia to relief the pain at an early stage of after no response to the medical treatment? 2/ Are repeated blocks more efficient than a single block?

Who can participate

Age range

18 Years – 85 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Acute zona diagnosed by the dermatologist o Acute skin rash with blisters in a limited area on one side of the body * Eruption * Unilateral * On dermatome between C5 and S2 * Age 18 to 85 years old, males and females * American Society of Anesthesiologists Score \[ASA \]grades I \& II * Patient who accepted to participate as volunteers and signed an informed consent Exclusion Criteria: * Psychiatric disease * Central nervous system disease or pre-existing neuropathy * Coagulation abnormalities or anti-coagulant treatment (heparins Anti vit K anti thrombin) * Contra indication to perform a peripheral nerve block or interfascial block * Infection of the skin overlying the puncture site of the block * Allergy to local anaesthetic or prednisolone * Contra indication to prednisolone * ASA III and IV * Morbidity Obese BMI \> 30 * Pregnant woman

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in pain intensity between baseline and the end of treatment

Timeframe: baseline - end of treatment at day 30

Trial details

NCT IDNCT04133142

SponsorVinmec Healthcare System

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-11-12

View on ClinicalTrials.gov More Zoster Without Complications trials