CompletedNot Applicable

Comparison of Autogenous Bone Graft and Screw Tent-Pole Technique on Atrophic Mandible

13 participantsStarted 2016-04-11

Plain-language summary

The purpose of the present study was to assess the effect of injectable platelet-rich fibrin (i-PRF) enriched with allograft on alveolar bone regeneration when compared with autogenous block bone graft, in the same participants. The study was designed as a split-mouth randomized controlled trial. The patients were randomly assigned to one of two surgical groups: the test group with i-PRF enriched particulate allograft using the screw tent-pole technique; and the control group with autogenous block bone harvested from the ramus area. All augmentation sites covered by leukocytes-PRF (L-PRF) membrane. The primary outcome variable of this study was the radiographic and histologic data collected at postoperative 6 months. The secondary outcome variable was nerve alterations and implant survival.

Who can participate

Age range

18 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients who refused to use a partially removable prosthesis and requested dental implant treatment, * Patients had bilateral, moderate or severe posterior atrophic mandible, * Patients had precluded conditions suitable for short dental implant. Exclusion Criteria: * Patients who had systemic diseases (osteoporosis, hemophilia, anemia, etc.), * Patients who required drugs (bisphosphonate or steroid therapy), * Patients who had a smoking habit, * Patients who had received radiation therapy within the last two years, * Patients who were under 18 years old, pregnant or lactating, * Patients who had a total platelet count lower than 150,000/mm3.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Assessment of radiological changes

Timeframe: Change of alveolar bone height at 6 months

Histological assessment

Timeframe: Postoperatively 6 months

Trial details

NCT IDNCT04133090

SponsorEge University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-10-08

View on ClinicalTrials.gov More Alveolar Bone Loss trials