ABPT in Secondary Pneumothorax With Persistent Airleak Study (NCT04132687) | Clinical Trial Compass
UnknownNot Applicable
ABPT in Secondary Pneumothorax With Persistent Airleak Study
Hong Kong35 participantsStarted 2019-09-10
Plain-language summary
This is a prospective clinical trial with each patient serving as his/her own control. Patients will be recruited in three different Hong Kong hospital. All patients at the recruitment centers with ongoing air leak after ≥ 3 days from the initial diagnosis of SSP will be approached by site investigators. Patient consented to enter the study will have their rate of air leak measured on day 3 (or after if enrolled later than day 3) byreplacing the conventional chest drain system with the digital chest drainage device (Thopaz).
Autologous blood patch will be instilled if the patient still has persistent air leak on day 5 of chest drain insertion ( or 48 hours of electronic chest drain measurement of airleak).
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* aged 18 years or older;
* radiographically proven pneumothorax and underlying lung disease (either pre-existing or shown in diagnostic imaging at presentation);
* chest tube inserted which still shows an air leak at day 5 (or later) after the first radiographic evidence of a pneumothorax.
Exclusion Criteria:
* inability to provide informed consent;
* a chest tube smaller than 12 F (because of the risk of blockage by blood)
* bilateral pneumothorax
* uncorrectable coagulopathy
* active or recent (within 6 weeks) pleural infection
* use of long term steroid or immunosuppressant
* septicaemia or active extrapleural infection (eg pneumonia)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is testing autologous blood patch therapy — which uses my own blood to try to seal an air leak — can you explain how that procedure actually works and whether it would be appropriate for my type of secondary pneumothorax?
2Since this trial doesn't have a standard phase label, what does that mean about how much safety and effectiveness data already exists for this blood patch approach, and how does that uncertainty compare to more established treatments for a persistent air leak?
3The trial's recruitment status is listed as unknown — do you know if this study is still actively enrolling patients, and if not, are there other similar studies or options I should consider instead?
4If a persistent air leak is the main problem being treated here, what are the standard-of-care alternatives — like surgery or other drainage techniques — and how would those compare to trying the blood patch therapy this trial is studying?
5What would participating in this trial actually involve for me day-to-day, such as how many procedures, hospital stays, or follow-up visits, and is that realistic given my current condition?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.