Rare Variation and Remote Gene Regulation of Osteoporosis Related Phenotypes in Han Chinesse (NCT04129671) | Clinical Trial Compass
UnknownNot Applicable
Rare Variation and Remote Gene Regulation of Osteoporosis Related Phenotypes in Han Chinesse
China3,000 participantsStarted 2019-04-29
Plain-language summary
Bone density is recognized as the most important factor to measure osteoporosis, and the prevalence of osteoporosis increases with age. Risk factors for osteoporosis include age, weight, exercise, diet, smoking and alcohol consumption. What's more, osteoporosis has a strong familial aggregation, and the genetic value of bone density is between 0.6 and 0.85. Therefore, it is necessary to conduct large-scale collection of population samples of osteoporosis fractures and relevant genetic studies.
Who can participate
Age range50 Years – 100 Years
SexALL
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Inclusion criteria
✓. From July 2018 to July 2021, patients admitted to the outpatient or inpatient clinic were diagnosed as primary osteoporosis fracture;
✓. Aged between 50 and 100;
✓. This fracture was not treated with any anti-osteoporosis drugs before
✓. Subjects will participate in the study voluntarily and have signed the informed consent
✓. Patients with clear mind and independent behavioral ability
Exclusion criteria
✕. Patients with malignant tumors are associated with bone metastases, such as lung cancer, prostate cancer, thyroid cancer, etc