rTMS to Enhance Cognitive Performance and Promote Resilience (NCT04123496) | Clinical Trial Compass
CompletedNot Applicable
rTMS to Enhance Cognitive Performance and Promote Resilience
United States38 participantsStarted 2019-11-21
Plain-language summary
The purpose of this study is to determine the most effective dose of brief, non-invasive brain stimulation (repetitive transcranial magnetic stimulation, rTMS) for improving cognitive functions such as attention and memory as well as to improve the ability to recover from stressful situations (stress resilience).
Who can participate
Age range
22 Years – 55 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. No history of mental or physical illness
. No implanted metal in the body
. College graduates (Associates degree or higher)
. Negative urine pregnancy test, if female subject of childbearing potential
. Able to read and understand questionnaires and informed consent
Exclusion criteria
. Any current psychiatric diagnosis or current Clinical Global Impression ratings of psychiatric illness \> 1
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Mean Score of Neurocognitive Performance (Fluid Cognition)
Timeframe: Baseline (Day 1)
2
Change From Baseline in Neurocognitive Performance at 1 Week Post Treatment (Fluid Cognition)
Timeframe: Post-treatment (within 1 week of completing rTMS)
3
Change From Baseline in Neurocognitive Performance at 1 Month Post Treatment (Fluid Cognition)
Timeframe: Post-treatment (within 1 month of completing rTMS)