Rhabdomyolysis is a potentially life-threatening syndrome characterized by breakdown of skeletal muscle, and leakage of intracellular substances such as myoglobin and creatine kinase (CK) into the circulation. The aetiological spectrum of rhabdomyolysis is extensive, and the clinical spectrum varies from a transient subclinical increase in CK activity to acute kidney injury (AKI) as a serious complication. There are no large prospective studies and only a few retrospective studies on rhabdomyolysis.
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Development of Acute Kidney Injury (AKI)
Timeframe: Change of creatinine from baseline (KDIGO 2012 guidelines) through hospitalization (average 1 week)
Kidney function after three months and development of Chronic Kidney Disease (CKD)
Timeframe: 3 months