This study will assess the safety and tolerability of multiple doses of BMS-963272 in obese but otherwise healthy participants.
Age range
18 Years – 60 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Maximum observed plasma concentration of BMS-963272 (Cmax)
Timeframe: Day 1, Day 14
Time of maximum observed concentration of BMS-963272 (Tmax)
Timeframe: Day 1, Day 14
Area under the concentration-time curve in one dosing interval (AUC(TAU))
Timeframe: Day 1, Day 14
Area under the concentration-time curve from time zero to the time of the last quantifiable concentration (AUC(0-T))
Timeframe: Day 14
Apparent total clearance of the drug from plasma after oral administration (CLss/F)
Timeframe: Day 14
Apparent volume of distribution at steady state (Vss/F)
Timeframe: Day 14
Average concentration at steady state (Cavg,ss)
Timeframe: Day 14
Half-life (T-HALF)
Timeframe: Day 14
Accumulation index (AI)
Timeframe: Day 14
Rate elimination constant (kel) of BMS-963272
Timeframe: Day 14
Area under the concentration-time curve (AUC) of triglycerides (TG) and fatty acids in response to the oral lipid tolerance test (oLTT)
Timeframe: Day 7, Day 15
Incremental AUC (iAUC) of TG and fatty acids in response to the oLTT
Timeframe: Day 7, Day 15