Effect of Prebiotics on the Gut Microbiome Profile and Beta Cell Function

Exclusion criteria

• ✕. Presence of severe, active disease that interferes with dietary intake or requires the use of chronic medication, except for well-controlled hypothyroidism and mild asthma not requiring oral steroids.
• ✕. Diabetes other than T1D (Known monogenic forms of diabetes, Type 2 diabetes)
• ✕. Chronic illness known to affect glucose metabolism (e.g. Cushing syndrome, polycystic ovarian disorder, cystic fibrosis) or taking medications that affect glucose metabolism (e.g. steroids, metformin)
• ✕. Psychiatric impairment or current use of anti-psychotic medication
• ✕. Any condition that, in the investigator's opinion, may compromise study participation or may confound the interpretation of the study results.
• ✕. Female participants of child-bearing age with reproductive potential, must not be pregnant and agree to use an effective form of birth control or be abstinent during the study period (see below)
• ✕. History of recurrent infections
• ✕. History of on-going infections or antibiotic treatment within the past three months