CompletedNot Applicable

Thumb Osteoarthritis: A Cross-Sectional Study of Mechanisms

United States31 participantsStarted 2021-02-26

Plain-language summary

This study examines carpometacarpal osteoarthritis (CMC OA) and aims to elucidate the biomechanical, neuromuscular, and somatosensory mechanisms that contribute to CMC OA symptoms by using orthopaedic biomechanics and quantitative pain testing. Completion of this study will provide a comprehensive dataset describing how movement strategies (muscle activity and joint posture) as well as experimental and clinical pain differ between individuals with CMC OA and age-matched controls.

Who can participate

Age range40 Years – 90 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * CMC OA Subjects: * female between the age of 40 to 90 years * end-stage CMC OA diagnosed by a board-certified clinician * Age-Matched Control: * female between the age of 40 to 90 years * no joint or muscle pain in the hand or wrist Exclusion Criteria: * All Groups: * pregnant women; minors (under age 18); mentally disabled; any persons incarcerated, on parole, on probation, or awaiting trial * individuals with concomitant musculoskeletal pathologies (other than osteoarthritis) in the hand or wrist, including distal radius fracture, contracture, trigger finger, and carpal tunnel * individuals with history of uncontrolled diabetes, rheumatoid arthritis, muscular dysfunction, or neurological disease

What they're measuring

Australian Canadian OA Hand Index (AUSCAN)

Timeframe: Baseline

Disabilities of the Arm, Shoulder, and Hand (DASH)

Timeframe: Baseline

Trial details

NCT IDNCT04104477

SponsorUniversity of Florida

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2023-12-31

Results submitted2024-05-29

View on ClinicalTrials.gov More Carpometacarpal Osteoarthritis trials