TerminatedNot Applicable

ICU Associated Weakness and Bedside Ultrasound Assessment

Stopped: Coronavirus pandemic halted in-unit enrolment and participation

Canada11 participantsStarted 2019-10-01

Plain-language summary

ICU-associated weakness is a common experience for people following a critical illness. It is associated with important patient and system-relevant outcomes. Diagnosing ICU-associated weakness can be challenging because making the diagnosis relies on volitional participation in strength testing by the patient in a very ill population that is often sedated or restrained. This study proposes to test if bedside ultrasound of tibialis anterior (a non-invasive test that doesn't require active participation by the patient) correlates with clinical whole-body weakness in critically ill patients admitted to an ICU with sepsis.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. adult patients (age \> 18 years);
✓. admitted to the ICU with a diagnosis of sepsis, and;
✓. an ICU duration of stay of greater than 4 days (two allow for serial assessments of muscle strength and size).

Exclusion criteria

✕. Any pre-existing diagnosis that would reasonably impact a participant's muscle bulk, strength, coordination, or ability to participate in the assessment
✕. Any activity orders or movement restrictions (including medical devices such as casts or external fixation devices) that would preclude accurate motor strength assessment.
✕. Dressings, casts, or medical implements that would preclude or impede ultrasound assessment of tibialis anterior muscle cross-sectional area in both legs.
✕. Patients who are "proned" or in positions that make assessing tibialis anterior with ultrasound or physical exam impractical.
✕. Re-admission to ICU within the same hospital stay.

What they're measuring

Correlation of tibialis anterior muscle atrophy development with whole-body strength

Timeframe: First two weeks of ICU admission

Trial details

NCT IDNCT04095533

SponsorUniversity of Calgary

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2020-04-01

View on ClinicalTrials.gov More Sarcopenia trials