Effects of Cerebral & Peripheral Electrical Stimulation on Pain and Function in CTS

Inclusion Criteria: * Males and females aged \>18 years and \<65 years. * Paresthesia, pain or vasomotor symptoms through the distribution of median nerve (persistence \> 2 months). * Positive result for Phalen's, Tinel's and/or carpal compression tests during physical examination. * Mild-to-moderate severity of CTS according to American Association of Neuromuscular \& Electrodiagnostic Medicine (AANEM) 2002 (mild: abnormal sensory peak latency \[≥3.5ms\] with normal motor distal latency \[\<4.4\]; moderate: abnormal sensory \[≥3.5ms\] and motor \[≥4.4ms\] latencies). Exclusion Criteria: * Previous history of wrist surgery * Presence of predisposing etiological factors for CTS (e.g., diabetes mellitus). * Trauma, neurological, psychiatric, rheumatic diseases, renal failure, pregnancy, hypothyroidism, and hyperthyroidism. * Presence of conditions that might cause numbness in the hand, including cervical radiculopathy, cervical ribs, plexopathy, and polyneuropathy. * Pharmacological treatment with oral steroids or non-steroidal anti-inflammatory drugs within the previous month. * Participation in a physical therapy program. * Administration of steroid injection(s) within the previous 6 months. * Previous treatment with TENS \<6 months. * Previous treatment with tDCS. * Use of pacemakers or other implanted devices. * Pregnancy or breastfeeding. * Refuse to participate.