IntelliCycleTM 2.0 Improved Patient-ventilator Asynchrony During PSV
China24 participantsStarted 2019-09-18
Plain-language summary
Pressure Support Ventilation use Expiratory triggering sensitivity (Esense) to transfer inspiration to expiration, the value of Esense is fixed. That may lead to asynchrony between humans and ventilators, making people uncomfortable and prolonging weaning time. Furthermore，trigger delay or inffective trigger happens frequently during insppiratory triggering. The ventilators have a compunter drived funcation of automatic adjustmen of inspiratory triger and cycling-off based on waveform, IntelliCycleTM 2.0. It will make the transforming more synchrony with humans. The objectibe of the present study is to detect the effect of automatic adjustmen of inspiratory triger and cycling-off based on waveform on patient-ventilator interation.
Who can participate
Age range18 Years – 85 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
✓. receiving invasive mechanical ventilation due to operation
✓. abdominal surgery, orthopedic surgery or gynecological surgery
✓. without respiratory system Comorbidity
✓. able to sustain PSV more than 1 h with inspiratory support ≤ 15 cmH2O.
✓. receiving invasive mechanical ventilation due to acute respiratory failure
✓. able to sustain PSV more than 1 h with inspiratory support ≤ 15 cmH2O.
Exclusion criteria
✕. age \< 18 or \>85 years,
✕. tracheostomy at time of inclusion,
✕. contra-indication for nasogastric tube insertion (e.g. history of esophageal varices, gastro-esophageal surgery in the previous 12 months or gastro-esophageal bleeding in the previous 7 days, INR ratio \> 1.5 , APTT \> 44 s, history of leukemia),
. neuromuscular disease affecting spontaneous breathing (e.g. history of acute central or peripheral nervous system disorder or neuromuscular disease with irregular spontaneous rhythm),