WithdrawnNot Applicable

Cardiac Risk Assessment Using Standard of Care Versus CTA and Heart Flow FFRct

Stopped: Essential staff for study execution left the institution and no suitable replacement could be found.

0Started 2023-06

Plain-language summary

Coronary Artery Disease (CAD) is the narrowing or blockage of the artery of the heart and is prevalent in end-stage liver disease. Consultation with cardiologist and stress tests are recommended to patients under consideration for liver transplant. The purpose of this study is to evaluate if Computed Tomography Angiogram (CTA) and CTA-derived Fractional Flow Reserve (FFRct) procedure influences decisions about further cardiac testing compared with Standard of Care (SOC) such as consultation by a cardiologist, Echocardiogram (ultrasound of the heart), Electrocardiogram (ECG) and stress tests.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. Patients with end-stage liver disease
✓. Patients undergoing cardiovascular risk assessment prior to liver transplantation -

Exclusion criteria

✕. Estimated Glomerular Filtration Rate (eGFR) \< 30 cc/min/1.73 m\^2 (unless patient is on dialysis or renal transplant is planned)
✕. Heart rate \> 90 bpm despite beta blocker therapy
✕. Body Mass Index (BMI) \> 40 plus chest obesity (i.e. truncal obesity and normal chest morphology is not an exclusion)
✕. Pregnant Women

What they're measuring

Change in clinical recommendation

Timeframe: within 2 weeks after SOC assessment

Trial details

NCT IDNCT04089969

SponsorCorewell Health East

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-06

View on ClinicalTrials.gov More Coronary Artery Disease trials