CompletedPhase 4

Vancomycin Dosage Strategy Based on a Trough Concentration Model

China66 participantsStarted 2019-10-01

Plain-language summary

Study design: Allocation: Randomized Endpoint classification: Efficacy study Masking: Open label Primary purpose: Treatment Primary endpoint: Incidence of reaching the target serum trough concentration Secondary endpoint: Clinical efficiency, Antibiotic use, acute kidney injury.

Who can participate

Age range60 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients with doubted or diagnosed Methicillin-resistant Staphylococcus aureus severe pneumonia, and need vancomycin treatment. * Sixty years and older. Exclusion Criteria: * younger than 60 years old * Accepted blood purification therapy * Pregnancy * Positive HIV antibody titre * Had known or suspected tuberculosis or other infections caused by fungi at baseline.

What they're measuring

The incidence of vancomycin therapeutic serum trough concentrations

Timeframe: before the fifth vancomycin dosage

Trial details

NCT IDNCT04088305

SponsorPeking University Third Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-05-31

View on ClinicalTrials.gov More Pneumonia, Staphylococcal trials