CompletedPhase 4

Short Term Effect of Vitamin D Supplementation on the Clinical Outcomes in Patients Undergoing Valve Replacement Surgery

Egypt86 participantsStarted 2017-04-01

Plain-language summary

This study evaluates the effect of Vitamin D supplementation on ICU and hospital LOS in patients undergoing valve replacement surgery. Half of the patients will receive Alfacalcidol, while the other half-the control group- will be exposed to the same environment without receiving alfacalcidol.

Who can participate

Age range18 Years – 65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * patients undergoing mechanical valve replacement surgery Exclusion Criteria: * combined valvular replacement surgery and Coronary Artery Bypass Graft (CABG) surgery * valvular replacement redo * valvular replacement surgery secondary to infective endocarditis * on dialysis * ALT levels 2-3 times higher than normal range * CHD, * impaired gastrointestinal function * indication for vitamin D supplementation within the prior month * hypercalcemia defined as total calcium \>10.4 mg/dl * hyperphosphatemia defined as serum phosphate \> 4.5 mg/dl * pregnancy and lactation.

What they're measuring

hospital length of stay

Timeframe: time to hospital discharge, up to 15 days

intensive-care unite length of stay

Timeframe: time to ICU discharge, up to 7 days

Trial details

NCT IDNCT04085770

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-02-26

View on ClinicalTrials.gov More Cardiac Valve Replacement Complication trials