Cam Type FAI is a Cause of Hip Pain in the Young Adult and a Precursor to OA (NCT04080466) | Clinical Trial Compass
UnknownPhase 2
Cam Type FAI is a Cause of Hip Pain in the Young Adult and a Precursor to OA
Canada58 participantsStarted 2021-02-20
Plain-language summary
An abnormally formed hip joint (cam deformity) is a major cause of osteoarthritis (OA). Individuals may not experience any symptoms until OA is severe due to extensive cartilage loss and changes in underlying bone. A series of studies showed that the cam deformity can lead to the development of OA if left untreated, thus strongly suggesting a causal relationship. Currently, the cam deformity that causes pain is surgically removed to relieve the pain and treat the associated cartilage damage. Recent studies have demonstrated that surgical treatment leads to bone and cartilage changes that were related to improved function and reduced pain.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Skeletally mature patient undergoing cam resection by hip arthroscopy with hip pain longer than 6 months
* Absence of arthritis (Tonnis Grade 0 or 1)
* Absence of dysplasia (LCEA \> 25°) or overcoverage (LCEA \> 39°)
* Alpha angle greater than 55° on multiplanar imaging
* Subject is over the age of 18 years old at time of enrollment
* Subject is willing and able to complete required study visits and assessments
* Subject is willing to sign the approved Informed Consent Form
Group 2 Inclusion Criteria:
* Normal femoral head neck contour and no evidence of dysplasia
* Subject is over the age of 18 years old at time of enrollment
* Subject is willing and able to complete required study visits and assessments
* Subject is willing to sign the approved Informed Consent Form
Exclusion Criteria:
* Prior joint replacement surgery in any lower-limb joint due to OA
* History of lower-limb joint or back injury in the last year that impairs mobility
* Metallic prosthesis
* Worked with metal, metal fragments in the eye
* Blood transmittable disease(s)
* In vivo devices (Aneurysm clip(s), Pacemaker, ICD, Implanted hearing device)
* Extreme claustrophobia
* Overweight or obese (BMI \> 30) and/or waist circumference \>102cm in men and \>88cm in women
* Diagnosis of Parkinson's or uncontrollable tremors
* Known history of early OA in the immediate family
* Pregnant, Breastfeeding, or planning to get pregnant
* Cognitive impairment that prevents accurate completion of…
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Assessment of [18F]-NaF as a biomarker of hip degeneration