WithdrawnNot Applicable

Profiling Fecal Samples for Selection of Donors of Feces

Stopped: COVID-19

0Started 2020-03

Plain-language summary

Fecal microbiota transplantation (FMT) represents a promising therapeutic in numerous clinical situations associated with dysbiosis. Today, this procedure is recommended in patients with recurrent Clostridioides difficile infections but beneficial effects of FMT have also been described in other diseases associated with intestinal dysbiosis …. A donor effect which could be related to the inter-individual variability of microbiota and microbiome leading to specific metabolic capacities may influence the efficacy of the procedure.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. Age ≥ 18 years
✓. Healthy volunteers
✓. Participant having been informed of the study and having sign a consent to participation
✓. Patient affiliated with a social security or beneficiary of such a social protection

Exclusion criteria

✕. Person subject to legal protection (guardianship, trusteeship, etc.)
✕. Chronic disease that can alter the intestinal microbiota: cancer or malignant disease, bowel disease, diabetes, hypertension, hypercholesterolemia, ....
✕. Presence in the 1st degree family of one of the chronic diseases mentioned above
✕. Blood in stools
✕. Chronic drug treatment likely to alter the intestinal microbiota
✕. Travel to a tropical country in the last 3 months or extended stay (\> 3 months) for less than 1 year
✕. Hospitalization abroad (\> 24h) in the last 12 months
✕. Hospitalization abroad (\> 24h) of a family member living under the same roof during the last 12 months

What they're measuring

Dosage of fecal samples with search for differentiated fecal profiles.

Timeframe: At 12 months

Trial details

NCT IDNCT04078581

SponsorAssistance Publique - Hôpitaux de Paris

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-06

View on ClinicalTrials.gov More Fecal Microbiota Transplantation trials