CompletedNot Applicable

The Effect of Body Mass Index In Relation To Menstrual Cycle Phase on Propofol Injection Pain

Egypt90 participantsStarted 2020-02-01

Plain-language summary

There are suggestions from experimental pain studies that pain perception in patients with severe obesity differs compared with individuals with lower BMI values, with a tendency for patients with severe obesity to be hypoalgesic - that is, to have reduced numerical pain scores to a variety of painful stimuli. That finding could be related to: associated reduced cognitive function (complex attention, verbal and visual memory, and decision making) in severe obesity. The purpose of this study is to determine differences between females' pain levels whether they are obese or non-obese, during different menstrual phases (premenstrual, postmenstrual and menopausal phases) through propofol injection pain given for induction of GA

Who can participate

Age range18 Years – 65 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 18 years - 65yor older, * physical status ASA I\&II Exclusion Criteria: * irregular menstrual cycle, * those who received hormonal therapy for any cause, * on oral contraceptive pills, * breast feeding, * pregnant, * history of total abdominal hysterectomy and/or bilateral salphingo-opherectomy. * patients who had difficulty in understanding the visual analogue scale (VAS)/ pain scoring systems, * renal or hepatic insufficiency, * anticipated difficult tracheal intubation, and * hypersensitivity to the study drugs. * Also, patients on antidepressants and analgesics

What they're measuring

VAS score

Timeframe: immediately after injection

Trial details

NCT IDNCT04078087

SponsorAin Shams University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2020-06-30

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