CompletedNot Applicable

The Psychophysiological Effect of Simulated and Terrestrial Altitude

Switzerland20 participantsStarted 2019-06-24

Plain-language summary

The aim of this study is to compare the psychophysiological effects of terrestrial altitude with a normobaric, hypoxic situation.

Who can participate

Age range18 Years – 50 Years

SexALL

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Inclusion Criteria: * Healthy, adults aged 18 to 50 years * No cardiovascular disease and / or surgery * no surgery on the cardiovascular system. * No current injuries and / or pain * Regular and adequate sleep * No terrestrial altitude of 1000 m exceeded last month (including flights) * No form of hypoxia exposed last month Exclusion Criteria: * Age over 50 years * current injuries of any kind and / or pain * Acute and / or chronic pain conditions Known general diseases (e.g., diabetes mellitus) * fear of hypoxia * fear of heights or sensitivity to terrestrial altitude * Regular use of medicines (also bought by yourself), except for contraceptives * Cardiovascular diseases or abnormalities * Anomalies of the blood analysis or ECG * Psychological disorders * pregnancy / lactation

What they're measuring

Oxygenation of the Brain

Timeframe: Baseline (participants seated for 15 minutes) and during the cognitive performance under normobaric hypoxia, hypobaric hypoxia, and control conditions (mean over time)

Oxygenation of the Blood

Timeframe: Continuously during the 15-minute seated baseline period before each trial (mean over 15min) and at the end of the step-up test (point measurement)

Mean Arterial Pressure

Timeframe: At the end of the 15-minute baseline seated period before each trial and at the end of the 3-minute submaximal step-test (Point measurements)

Heart Rate

Timeframe: at baseline and the end of the submaximal step test (point measurements)

Concentration of Blood Lactate

Timeframe: at the end of 15min baseline period and the end of the step-up test (point measurements)

Sleep Quality

Timeframe: Before the cognitive performance test (point measurement)

Altitude Sickness

Timeframe: After performing the 3-min step-test (point measurment)

Trial details

NCT IDNCT04075565

SponsorUniversity of Applied Sciences and Arts of Southern Switzerland

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-03-31

Results submitted2025-08-19

View on ClinicalTrials.gov More Hypoxia trials